matrix linear models for high-throughput genetic screens

A flexible and computationally efficient approach for analyzing high throughput chemical genetic screens

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speeding up eqtl scans in the bxd population

To facilitate interactive use of genotype-phenotype relationships in the BXD population, we sought to speed up eQTL scans. We were able to decrease runtimes to approaching real-time computation.

current collaborations

summary of current collaborations

fitting penalized multivariate linear models

We have developed a fast algorithm for fitting L1-penalized multivariate linear models for high throughput data

mapping function-valued traits

Supporting information for Xiong et. al. (2011)

qtl mapping from an information perspective

Supporting information for Sen et. al. (2005)